Alexander M. Reyzelman, D.P.M., F.A.C.F.A.S.
California School of Podiatric
Medicine
2299 Post St. Ste. 205
San Francisco, California 94115
(415) 292-0638
(415) 292-0718 fax
Email: areyzelman@samuelmerritt.edu
Education:
1991-1995 California
College of Podiatric Medicine
San Francisco, CA
Doctor
of Podiatric Medicine
1987-1991 University
of San Francisco
San Francisco, CA
Bachelor
of Science in Biology
Postgraduate
Training:
1995 – 1996 Primary
Podiatric Medical Residency
1996 - 1998 Podiatric
Surgical Residency
Univeristy
of Texas Health Science Center at San Antonio
2004 Intensive
one week course in peripheral nerve surgery
Work
Experience:
1998 to present Private
practice, San Francisco, CA,
Castro Valley, CA
1999 to 2001 Clinical
Director, Pacific Coast Wound Care, San Francisco, CA
2000 to 2001 Co-chair
Department of Medicine, California College of Podiatric Medicine, San Francisco, CA
9/2001-2009 Assistant
Professor, Chairman, Department of Medicine, California School of Podiatric
Medicine at Samuel Merritt College
7/2009- present Associate
Professor, Chairman, Dept of Medicine, California School of Podiatric Medicine
at Samuel Merritt University.
Hospital Staff
Appointments:
1999 to present California Pacific Medical Center
San Francisco, CA
1999 to present Eden Hospital
Castro Valley, CA
2008 to present St.
Mary’s Hospital
San Francisco, CA
2008 to present St. Rose Hospital
Hayward, CA
1998
to 2000 Pacific Coast Hospital
San Francisco, CA
1999 to 2007 Mercy San Juan Hospital
Carmichael, CA
1998 to 2001 Mount Zion Hospital
San Francisco, CA
1995 to 1998 University Hospital (Residency)
San Antonio, Tx
1995 to 1998 Audie L. Murphy Veterans Administration Hospital (Residency)
San Antonio, Tx
Licensure:
1996-98 Texas
1998 to present California
2005 to present Nevada
Certification:
2005 to present Board
Certified in Foot Surgery
1995 to 1999 Advanced
Cardiac Life Support
1995 to Present Basic
Life Support
1998 to Present QME,
AME
Professional
Affiliations:
1995 to Present American
Podiatric Medical Association
1998 to Present California Podiatric Medical Association
1995 –1998 Texas
Podiatric Medical Association
1995 to Present American College of Foot and Ankle Surgeons
1995 to Present American
Diabetes Association
Lectures and
Workshops:
1995-1996 -Peripheral
nerve injuries. UTHSC-SA
-Tendon
injury and surgery. UTHSC-SA
-Radiographic
analysis of a bunion UTHSC-SA
1996-1997 -Differential
diagnosis of lower extremity edema. Bandera Hill Country
Seminar, Bandera, Texas.
-Diabetic
footwear post amputation. Vascular surgery grand rounds
-Implant
arthroplasty of the great toe joint. UTHSC-SA
-Klippel
Trenuanay Syndrome. Podiatry grand rounds.
1997-1998 -Foot
burns in patients with diabetes. Podiatry grand rounds
-Isolated
subtalar arthrodesis vs. triple arthrodesis. UTHSC-SA
-Instructional
course on interpretation of non-invasive vascular
arterial
studies and lower extremity angiograms. Post-graduate
Diabetic
Foot Course.
-Instructional
hands-on course on foot amputations. Post-graduate
Diabetic
Foot Course.
-Interpretation
of non-invasive arterial study as it relates to healing
potential.
Bandera Hill Country Seminar, Bandera, Texas.
-Immaging
modalities of the diabetic foot. NPMA
Conference, San Antonio, Texas.
-Footwear and insoles for diabetic patient
workshop. Centers of
Wound
Healing Excellence: Improving Outcomes with New
Technologies,
UTHSC-SA
1999 -Surgical indications for
Charcot’s arthropathy, Limb salvage in
diabetic patients, Clinical application of non-invasive arterial
studies. Mid-Atlantic Podiatric Medical Association, West Virginia
2000 -Diabetic
workshop, Super Seminar 2000, Las Vegas Nevada.
-Complicated
wound panel, Western Podiatric Medical Congress,
Anaheim, CA.
-Wound Care, The Multidisciplinary Approach. Essential of
Practice Seminar, San Francisco, CA.
2001 -Diabetic workshop. Super
Seminar 2001 Las Vegas Nevada
-Moderator for the Wound Care Track at the Super Seminar, Las Vegas Nevada
-Wound Bed Preparation. San Francisco, CA
-Advances in Wound Care Technologies. Noon Conference Eden Hospital, Castro Valley CA.
-Diabetic Foot. Medicine Grand Rounds, California Pacific Medical Center, San Francisco CA.
-Bioengineered Skin Equivalents. Alameda County Podiatric Medical
Association, San Leandro CA
-Validation of Multidisciplinary Approach. Western Podiatric Medical
Congress, Anaheim CA.
-Differential Diagnosis and Assessment of Lower Extremity ulcerations.
Sutter Visiting Nurses, Vallejo CA
-Wound Bed Preparation. WOCN Association, Sacramento CA
2002 -Bioengineered
Skin Equivalents: Dermagraft, SuperSeminar 2002, Las Vegas, NV
-Lower Extremity Vascular Evaluation in a Diabetic Patient. Super
Seminar 2002, Las Vegas, NV
-Diabetic/Wound Care Workshop, Super Seminar 2002, Las Vegas, NV
-Vacular Compromised Digit, Essentials of Practice 2002
-Pathogenesis of Diabetic Foot Ulcerations, University of Texas Diabetic Foot Conference, San Antonio, TX 2002.
-Diabetic Foot Infections, San Francisco and San Mateo County Podiatry Association, 2002
-Diabetic Foot Infections, Santa Clara County Podiatry Association,
2002
2003 -Diabetic
Foot Infections, Alameda and Contra Costa County Podiatry Association, 2003
-Approach to lower extremity ulcerations,
Sutter Visiting Nurses Association, 2003
-Diabetic
Wound Care workshop, Super Seminar 2003,
Las Vegas, NV
-Advances in Wound Care. The Role of the VAC., The Western Seminar
2003, Anaheim, CA
-Management of the Diabetic Foot Ulcerations, Modesto and Stockton Podiatry Association, Stockton, CA 2003.
-Diabetic Foot Infections, Sacramento Podiatry Association, Sacramento, CA 2003
2004 -Diabetic
Wound Care Track, Super Seminar 2004
-The
Role of the VAC, The Western 2004, Anaheim, CA
-Diabetic Wound Care Update, Alameda Contra Costa Podiatry Association,
CA
2005 -Transmetatarsal
Amputations, The Western 2005, Anaheim, CA
-Patient Care and Research, The Western
2005, Anaheim, CA
-Peripheral Neuropathy and Its Effects on the Lower
Extremity. UCSF, SF, CA.
-Update on the use of Antibiotics in Treatment of Diabetic Foot
Infections, San Francisco, CA
2007 -Management
of Diabetic Foot Infections. St. Mary’s Hospital Department of Podiatry.
April 2007.
-Management of the Diabetic Foot. California Pacific Medical Center, Grand Rounds, June 2007
-Treatment of Diabetic Foot Infections. Las Vegas Nevada August 2007.
-Treatment of Diabetic Foot Infections. University Medical Center Grand Rounds, Las Vegas Nevada, November 2007
-Management of Diabetic Foot Infections. UCSF Surgery Dept. July 2007
-Systemic Approach to Diabetic Foot Infections, Diabetic Foot Update
Conference, University of Texas Health Science Center at San Antonio, December
2007
-Teaching Points in Performing Foot Amputations, Diabetic Foot Update
Conference, University of Texas Health Science Center at San Antonio, December
2007
2008 -Common
Foot Problems in the Emergency Department, Eden Hospital Emergency Department.
-Pathophysiology
of the Diabetic Foot Ulcerations. Pacific Coast Region of the WOCN, Sacramento, CA.
2009 Using Skin
Expansion Device in Lower Extremity Wounds, 1st Annual Wound Care
Conference, Oakland, CA
Leadership:
2009-present Associate
Professor, Chair Department of Medicine, California School of Podiatric
Medicine at Samuel Merritt University
2001-present Assistant Professor, Chair Department of
Medicine, California School of Podiatric Medicine
2000 – 2001 Co-chair,
Department of Medicine, California College of Podiatric Medicine, San Francisco, CA
2003- present Board
of Editorial Advisors for Podiatry Today
2000 – 2003 Editor
of Diabetes Watch column Podiatry Today journal.
1997 – 1998 Administrative
and academic chief resident
Department
of Orthopaedics/Podiatry Service
University
of Texas Health Science Center at San Antonio
1994-1995 President
of Health and Honors Fraternity at the University of San
Francisco
Research/
Completed
Clinical Trials Primary Investigator for: An Open Label,
Multicenter Study to Evaluate The Use of Dermagraft in Patients with Diabetic
Foot Ulcers. (IDE), Advanced Tissue Sciences. Completed -12/2001.
Primary
Investigator for: A Phase III, Prospective, Randomized, Comparative Study of
Drug XXX to placebo in subjects with acute pain following bunionectomy
surgery. Completed- 10/2000.
Primary Investigator for: “A Phase III, Prospective, Randomized,
Stratified, Comparative Study of Next Generation Cover Dressing Versus Two
Competitive Foam Dressings in the Management of Venous Leg Ulcers” Convatec.
Completed-6/29/02.
Primary Investigator for: “A Phase IV Study of Aquacel Ag Dressing
Versus Saline-Moistened Gauze in the Management of Diabetic Foot Ulcers”
Completed 2004
Primary Investigator for: “A Comparative Prospective, Randomized
Double-Masked, Parallel Group, Controlled Trial of Celleration Mist Therapy
System (MTS) Versus Sham Control When Added to Standard of Care in the
Treatment of Diabetic Neuropathic Ulcers”, Completed 2004
A Prospective, Randomized, Controlled, Multi-center Pivotal Trial of
AutoloGel™ Versus Control When Added to the Standard of Care in the
Treatment of Non-healing Diabetic Foot Ulcer, Completed 2005.’
Primary Investigator for: “A Clinical Trial to Assess the Efficacy and
Safety of Cefdinir for the Treatment of Uncomplicated Skin and Skin Structure
Infections in The Diabetic Foot.” Completed 2005.
Primary Investigator for: “A Randomized Controlled Multicenter Trial of
Vacuum Assisted Closure Therapy in the Treatment and Blinded Evaluation of
Venous Stasis Ulcers”
Primary Investigator for: “A Trial Comparing topical antifungal agents
in the treatment of tinea pedis.
Primary Investigator for “A Confirmatory Study to Evaluate The Safety
and Efficacy of Cryopreserved Bilayered Cellular Matrix (Orcel) For the
Treatment of Venous Ulcers”
Primary Investigator for: “A Phase 3, Randomized, Double-Blind,
Multinational Trial of Intravenous Telavancin Versus Vancomycin for Treatment
of Complicated Gram-Positive Skin and Skin Structure Infections with a Focus on
Patients with Infections Due to Methicillin-Resistant Staphylococcus Aureus.
Primary Investigator for: “Linezolid in the Treatment of Subjects with
Complicated Skin and Soft Tissue Infections Proven To Be Due to
Methicillin-Resistant Staphylococcus Aureus”
A Prospective Randomized Trial in the Treatment of Subjects with
Onychomycosis.
Primary Investigator for “A Multi-Center, Double-Blind, Randomized
Study Assessing the Efficacy of a drug for Diabetic Peripheral Neuropathy.
KCI VAC Protocol VAC2001-08, “A Randomized, Controlled Multicenter
Trial of Vacuum Assisted Closure Therapy in the Treatment and Blinded
Evaluation of Diabetic Foot Ulcer”.
Primary Investigator for “A Multi-Center, comparator trial, comparing
two different compression bandage systems for venous leg ulcers”. 3M
Corporation
A Randomized, Blinded-Assessor, Controlled Study of NVC-101 in the
Treatment of Chronic Non-Healing Venous Stasis Ulcers.
A Multicenter, randomized study of the safety and preliminary efficacy
of topical low-dose nicotine gell (XXX) in patients with plantar diabetic foot
ulcers
Primary Investigator for “A Multi-Center, Double-Blind, Randomized,
Parallel, Vehicle-Controlled Dose-Ranging Study Assessing the Safety and
Efficacy of (XXX) Gel Versus Matching Vehicle Gel When Applied Topically for
Three Months to Subjects with Diabetic, Neuropathic, Foot Ulcers”
“Pivotal Study to Evaluate the Efficacy and Safety of Dermal-Living
Skin Replacement (XXX) in the Treatment of Chronic Diabetic Foot Ulcers XXX-2004”.
A Prospective, Randomized, Comparative Parallel Study of Acellular Matrix Wound Dressing In the Management of Diabetic Foot
Ulcers
A Prospective, Multi-Centre, Double Blind Randomized Placebo-Controlled
Clinical Study to Evaluate the Safety and Efficacy of (XXX) in a Phase III
Trial with Four-Layer Therapeutic Compression, For the Treatment of
Non-Infected Skin Leg Ulcers, Due to Venous-Insufficiency”
A Prospective, Multi-Center, Open-Label Study to Evaluate the Safety
and Effectiveness of Healadex Wound Dressing in the Treatment of Chronic Ulcers
of the Lower Extremities, Protocol #XXX
A Double-Blind, Randomized, Parallel-Group, Vehicle-Controlled,
Multi-Center Study to Evaluate the Safety and Clinical Equivalence of a Generic
Ciclopirox Gel 0.77% to Loprox® Gel (Ciclopirox) 0.77% in the
Treatment of Interdigital Tinea Pedis,
A Multicenter, randomized, double-blind, comparison study of the safety
and efficacy of a once-daily dose of tigecycline versus Ertapenem for the
treatment of foot infections in subjects with diabetes.
A Randomized, Controlled, Open-Label Study to Investigate the Safety
and Efficacy of a Topical XXX (XXX) in Combination with Antimicrobial Therapy
Compared to Antimicrobial Therapy Alone in Diabetic Patients with Moderately
Infected Lower Extremity Skin Ulcers”.
Clinical Trials
In Progress
“A Prospective, Randomized, Controlled, Unmasked, Multiple Treatment,
Multi-Center Clinical Trial to Evaluate the Efficacy and Safety of an
Interactive Wound Dressing containing (XXX) versus Conventional Wound Therapy
for the Treatment of Diabetic Foot Ulcers.
Cross-Sectional Study: Comparing Pressure Specified Sensory Device vs.
Electrodiagnostic Studies in diagnosing Tarsal Tunnel Syndrome.
Prospective study comparing injection technique in patients with
plantar fasciitis. Medial vs. Plantar approach.
Use of the dermaPACE™
(Pulsed Acoustic Cellular Expression) Device in Conjunction with Standard of
Care in the Treatment of Diabetic Foot Ulcers”
Evaluation of a Medical Food for Chronic Wounds of the Lower Extremity
in Patients with Diabetes. Multicenter trial.
A Phase II Randomized, Double Blind,
Placebo Controlled Dose Finding Study Investigating the Efficacy of (XXX) in
Venous Leg Ulcers
Consulting:
Medicis Laboratories, Podiatry Advisory
Panel, 2002
Eli
Lilly, Neuropathy Advisory Panel, 2004
Wound
Care Technologies Inc., 2008- present
Aalnex
Inc. 2008- present
Publications:
Day, R.D., Reyzelman, A., Harkless, L.B.,
Evaluation and Management
of the Interdigital Corn: A Literature Review. Clin Pod
Med Surg 13:2, April, 1996.
Reyzelman,
A.M., Van Gils, C, Hardin, T.C., Vayser, D.J., Harkless,
L.B.,Vancomycin-resistant Enterococci (VRE) Osteomyelitis
in the Foot: A Case Report. J. Am. Pod. Med. Assoc.
87:9, September 1997.
Felder-Johnson,
K.L., Reyzelman, A.M. “Foot and Ankle
Trauma”, Foot and Ankle Secrets, 1st
Ed. Hanley & Belfus,
Philadelphia , PA 1998.
Reyzelman, A.M., Lomba, M.R., Vayser,
D.J., Day, R.D., Burnett, O.E., Central Pain Syndrome with Manifestations in
the Foot: A Case Report and Literature Review. J. Amer. Pod. Med. Assoc. 88:5,
May 1998.
Reyzelman,
A.M., Armstrong, D.G., Hadi, S.A., Vayser, D.J.,
Husain,
S.K., Harkless, L.B., Emergence of Non-Group A
Streptococcal
Necrotizing Diabetic Foot Infections. J. Amer. Pod.
Med.
Assoc. 88:6, June 1998.
Morgan, C.B., Reyzelman, A.M., Cai, T.H., Harkless, L.B., Pre-operative
Assessment of Transplant Patient: J Foot & Ankle Surgery. 37:4,
July/August 1998.
Reyzelman, A.M., Hadi, S.; Armstrong, D.G., Limb Salvage with Chopart’s
Amputation and Tendon Balancing: J. Amer. Pod. Med. Assoc. 89:2, February 1999.
Reyzelman, A.M., Lipsky, BA., Hadi, S., Harkless, L.B., Armstrong DG.
The Increased Prevalence of Severe Necrotizing Infections Caused by Non-Group A
Streptococci. J. Amer. Pod. Med. Assoc. 89:9, September 1999
Steinberg, J.S., Reyzelman, A.M.: The Diabetic Foot:A
Multidisciplinary Team Approach. Podiatry Today 1999
Reyzelman, A.R., Tuthill, J.: Management of Diabetic Wounds and
Infections, Home Health Care Consultant, 7:4 April 2000.
Reyzelman, A.R., Loveland, L.J., Melillo, T.C.: Tendon Rebalancing
Improves Chopart Outcomes. Biomechanics, May 2000.
Loveland, L.J.,
Reyzelman, A.M.: Why Tendon Balancing is Essential For Amputation of The
High-Risk Diabetic Foot. Podiatry Today, May 2000
Reyzelman, A.M., Trombello, K.A., Vayser, D.J., Armstrong, D.G.,
Harkless, L. B.: Are Antibiotics Necessary in the Treatment of Locally
Infected Ingrown Toenails? Arch. Fam. Med. 9:Sept/Oct. 2000.
Jansma, J., Van Voris, K., Reyzelman, A.M: Management of Diabetic
Wounds and Infections in the Elderly Patient. Clinical Geriatrics. 9:7, June
2001
La Fontaine, J., Reyzelman A.M., Rothenberg, G., Husain, K., Harkless,
L.B.: The Role of Revascularization in Transmetatarsal Amputations: J. Am. Pod.
Assoc. 91:10, November/December 2001
Reyzelman, A., Tidwell, A.: Expert’s Tips on Wound Bed Preparation:
Podiatry Today July 2003.
Reyzelman, A.: Bracing and Orthotics. Guest Editor. Foot and Ankle
Quarterly The Seminar Journal. Vol 16:4 Winter 2004.
Reyzelman, A.: Current Trends in Performing Matrixectomies
Podiatry Today, December 2005.
Reyzelman, A., Fiorito, J., Hoover, C., Brewer, M.: Key Insights on
Lower Extremity Nerve Testing, Podiatry Today, October 2007
Moffatt, C.J., Edwards, M.C., Treadwell, T., Miller, M., Shafer, L.,
Sibbald, G., Brassard, A., McIntosh, A., Reyzelman, A., Price, P., Merkel, K.,
Walters, S., Harding, K.A. A randomized controlled 8 week crossover clinical
evaluation of the 3M Coban 2 Layer Compression System versus Profore to
evaluate the product performance in patients with venous leg ulcers., Int Wound
J 2008;5:267-279.
Reyzelman AR, Crews RT, Moore JC, Moore L, Mukker
JS, Offutt S, Tallis
A, Turner
WB, Vayser D, Winters C, Armstrong DG, “Clinical Effectiveness
of an
Acellular Dermal Regenerative Tissue Matrix Compared to Standard
Wound
Management in Healing Diabetic Foot Ulcers: A Prospective,
Randomized,
Multi-Center Study, Int Wound Journal, 2009, In Press
Poster
Presentations:
Clinical
Effectiveness of an Acellular Dermal Regenerative Tissue Matrix Compared to
Standard Wound Management in Healing Diabetic Foot Ulcers: A Prospective,
Randomized, Multi-Center Study. Presented at DFCON, Los Angeles, CA 3/2009.
Continuous
External Tissue Expander For Closure of Lower Extremity Wounds. A Case Series.
Presented at DFCON, Los Angeles, CA, 3/2009